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Introduction to the Prenatal DNA Paternity test on maternal blood samples
The current available techniques for prenatal diagnosis (CVS and amniocentesis) are invasive and carry with their use
a small but significant chance of miscarriage. As a result, the current standard care offers an invasive prenatal test only to those
women whose risk of chromosomal or genetic abnormalities are greater than or equal to the risk of a procedure-related loss.
The recent discovery of the presence of fetal DNA and fetal cells in maternal blood has offered new approaches to non-invasive prenatal diagnosis.
The concentration of fetal DNA in maternal blood was found to be much higher than that present in the cellular fraction.
By analyzing DNA profiles based on sets of specific markers, the laboratory is able to compare fetal DNA with genetic profiles of the
mother and alleged fathers. This webpage explains in details how and when you can do the non-invasive prenatal paternity test. For more information about non-invasive and invasive prenatal paternity tests, click here.
Advantages of fetal DNA analysis in the maternal blood
1. Analysis of fetal DNA and fetal cells in maternal blood samples is a screening test that is a non-invasive prenatal
procedure and poses no risks to the mother or the fetus. The non-invasive prenatal DNA paternity testing is based on the comparison of
genetic profiles of the fetal DNA, mother's blood and samples from the alleged fathers.
2. This prenatal non-invasive DNA paternity testing is relatively inexpensive in comparison to invasive techniques such as CVS
or amniocentesis.
To learn more, read Misconceptions about the technology and read an article in the Science magazine about the non-invasive prenatal technology.
Timing for the test
Using DNA test from Prenatal Genetic Center, prenatal DNA paternity can be performed after the 14th
weeks of gestation.
Results
The procedure takes 12 business days, and the final report contains one of the following results:
- The Alleged Father cannot be excluded as the biological father of the fetus based on the samples submitted from the mother and the alleged
father and the DNA extracted from the population of fetal cells;
- The Alleged Father is excluded as the biological father of the fetus based on the samples submitted from the mother and the alleged
father and the DNA extracted from the population of fetal cells.
Sensitivity and specificity of the test
Sensitivity and specificity of the detection of cell-free fetal DNA at 14 weeks of gestation for properly collected
maternal blood samples is more than 99%. We strongly recommend testing all alleged fathers that are involoved in your case.
Price for the Prenatal DNA Paternity test
Total price of laboratory DNA testing for prenatal DNA paternity test on blood is $990.00 (US). The cost includes
the diagnostic laboratory test, telephone consultations, sample collection kit, and final laboratory report. Please make sure that the
payment for the non-invasive prenatal DNA paternity is included in the form of money order, VISA, Master Card or American Express. A non-refundable
deposit of $200.00 is required to initiate the scheduling process and will be applied towards the case. The balance must be paid in
full before we can release the DNA test results. All prices are in US dollars.
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